EPIDEMIOLOGY OF DIPHTERIA IN PURWAKARTA REGENCY INDONESIA

Authors

  • Siwi Pramatama Mars Wijayanti Department of Public Health, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto
  • Alfianti Nur Fadillah Department of Public Health, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto

DOI:

https://doi.org/10.26555/eshr.v1i1.935

Keywords:

Bacteria, Diptheria, Epidemiology

Abstract

Background: Diphtheria is considered as a neglected disease since it was successfully eliminated in many countries. However, there were several sporadic re-emergence cases of Diphtheria and the peak was outbreak in Indonesia in 2017.  This research was a descriptive study aimed to explore epidemiology of diphtheria by person, time and place in one of diphtheria endemic area.

Methods: This was a descriptive study with cross sectional design in Purwakarta Regency, West Java, Indonesia in 2018. Several data were collected in this study such as diphtheria cases by age, time of occurrence, gender, place and immunization status. The data was collected from Purwakarta Health Office. It was the data from the year of 2015-2017. The data was analysed by using descriptive analysis with percentages displayed in graphs and tables.

Results: This study reveals that Purwakarta regency is an endemic area of diphtheria with fluctuated cases since 2015-2017. More cases of diphtheria occurred from September to December in rainy season. More cases suffered by children in 5-9 years old, however, this disease also infected adult population. The area with high diphtheria cases in this study also areas with high population densities which is conducive for C diphteriae transmission. Low coverage of immunization is highlighted in the result of this study, which could explain why diphtheria cases occurred continuously in this area.

Conclusions: High number of diphtherias in this area should be an awareness for local health officer to do an effective preventive effort such as increasing the coverage of vaccination. Furthermore, optimizing the role of religious and community leader should be made to support diphtheria vaccination programs.

References

Both L, Collins S, de Zoysa A, White J, Mandal S, Efstratiou A. Molecular and epidemiological review of toxigenic diphtheria infections in England between 2007 and 2013. Journal of clinical microbiology. 2015;53(2):567-72.

Efstratiou A, George RC. Laboratory guidelines for the diagnosis of infections caused by Corynebacterium diphtheriae and C. ulcerans. World Health Organization. Communicable disease and public health. 1999;2(4):250-7.

McEvoy P, Hadfield TL, Polotsky Y, Yakovlev AA, Tzinserling VA. The Pathology of Diphtheria. The Journal of Infectious Diseases. 2000;181(Supplement_1):S116-S20.

Harapan H, Anwar S, Dimiati H, Hayati Z, Mudatsir M. Diphtheria outbreak in Indonesia, 2017: An outbreak of an ancient and vaccine-preventable disease in the third millennium. Clinical Epidemiology and Global Health.

Husada D, Puspitasari D, Kartina L, Setiono P, Moedjito I, Kartika B. Six-Year Surveillance of Diphtheria Outbreak in Indonesia. Open Forum Infectious Diseases. 2017;4(Suppl 1):S244-S.

Murhekar M. Epidemiology of Diphtheria in India, 1996-2016: Implications for Prevention and Control. The American journal of tropical medicine and hygiene. 2017;97(2):313-8.

M R, M M. Diphtheria in Andhra Pradesh-a clinical-epidemiological study2013.

Fares A. Factors influencing the seasonal patterns of infectious diseases. International journal of preventive medicine. 2013;4(2):128-32.

Khetsuriani N, Zakikhany K, Jabirov S, Saparova N, Ursu P, Wannemuehler K, et al. Seroepidemiology of diphtheria and tetanus among children and young adults in Tajikistan: nationwide population-based survey, 2010. Vaccine. 2013;31(42):4917-22.

Kitchin NR. Review of diphtheria, tetanus and pertussis vaccines in clinical development. Expert review of vaccines. 2011;10(5):605-15.

Imdad A, Tserenpuntsag B, Blog DS, Halsey NA, Easton DE, Shaw J. Religious exemptions for immunization and risk of pertussis in New York State, 2000-2011. Pediatrics. 2013;132(1):37-43.

Wielders CC, van Binnendijk RS, Snijders BE, Tipples GA, Cremer J, Fanoy E, et al. Mumps epidemic in orthodox religious low-vaccination communities in the Netherlands and Canada, 2007 to 2009. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2011;16(41).

Shrivastwa N, Gillespie BW, Kolenic GE, Lepkowski JM, Boulton ML. Predictors of Vaccination in India for Children Aged 12-36 Months. American journal of preventive medicine. 2015;49(6 Suppl 4):S435-44.

Muhamad Ramdan I, Susanti R, Hayati Ifroh R, Noviasty R. Risk factors for diphtheria outbreak in children aged 1-10 years in East Kalimantan Province, Indonesia2018. 1625 p.

Quick ML, Strebel PM, Sutter RW, Wooten KG, Kobaidze K, Malakmadze N, et al. Risk Factors for Diphtheria: A Prospective Case-Control Study in the Republic of Georgia, 1995-1996. The Journal of Infectious Diseases. 2000;181(Supplement_1):S121-S9.

Mardiana DE. The Influence of Immunization and Population Density to Diphtheria's Prevalence in East Java. 2018. 2018;6(2):8.

Podavalenko AP. Estimating the Complication Risk of Epidemic Situation with Diphtheria in Ukraine2018. 26-33 p.

Downloads

Published

2019-09-09

Issue

Section

Research Article