Prevalence of Metabolic Syndrome Among Patients with Type 2 Diabetes at the Bon Samaritain University Hospital Complex in N’Djamena, Chad
DOI:
https://doi.org/10.26555/eshr.v7i2.12641Keywords:
Metabolic Syndrome, Abdominal Obesity, Hypertension, ChadAbstract
Introduction: The Metabolic Syndrome (MS) is characterized by the presence of at least three of the following five factors: abdominal obesity, hypertriglyceridemia, low HDL-cholesterol, glucose intolerance or type 2 diabetes, hypertension. It is relatively common with a prevalence that increases with age and predisposes to the occurrence of cardiovascular complications, hence the motivation of this study, the aim of which was to determine its prevalence in a Chadian population.
Method: We conducted a prospective study involving 115 subjects aged 20 to 80 received at the Biochemistry laboratory as part of a monthly visit. The anthropometric and clinical data were recorded, and the biochemical parameters were analyzed on the PENTRA C400 automaton. The MS was defined according to the criteria of the NCEP-ATP III (2001). All of these data were analyzed using Excel 2013 and IBM SPSS software.
Results: in our study the prevalence of MS is 72.2% of cases with a female predominance of 86.15% and it increases with age. The most frequent components of the metabolic syndrome were abdominal obesity (71%), arterial hypertension (45%), hypo HDL-cholesterol.
Conclusion: our results show a high prevalence of MS and its main components which are abdominal obesity, arterial hypertension, hypo HDL-cholesterol, explaining in parallel a high level of cardiovascular risk. Management should be multidisciplinary to optimize the risk of chronic complications.
References
Punthakee Z, Goldenberg R, Katz P. Definition, Classification and Diagnosis of Diabetes, Prediabetes and Metabolic Syndrome. Canadian Journal of Diabetes. 2018;42:S10-S15. doi:10.1016/j.jcjd.2017.10.003
Zampaligré I. Profil épidémiologique du syndrome métabolique chez les volontaires au dépistage du diabète sucré dans la ville de Bobo-Dioulasso (Burkina Faso).
Gamma-glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort - PubMed. Accessed May 18, 2023.
Masson E. Nouveaux mécanismes physiopathologiques du Syndrome Métabolique : implication des récepteurs nucléaires orphelins ? EM-Consulte. Accessed March 1, 2025.
The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes - PubMed. Accessed March 1, 2025.
Diabetes mellitus type 2 in urban Ghana: characteristics and associated factors | BMC Public Health | Full Text. Accessed March 1, 2025.
Nsiah K, Shang Vo, Boateng Ka, Mensah F. Prevalence of metabolic syndrome in type 2 diabetes mellitus patients. Int J App Basic Med Res. 2015;5(2):133. doi:10.4103/2229-516X.157170
Ferrannini E. Physiological and metabolic consequences of obesity. Metabolism. 1995;44(9 Suppl 3):15-17. doi:10.1016/0026-0495(95)90313-5
Protéine C-réactive, syndrome métabolique et risque d’événements cardiovasculaires incidents : suivi de 8 ans de 14 719 femmes américaines initialement en bonne santé - PubMed. Accessed March 1, 2025.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287(3):356-359. doi:10.1001/jama.287.3.356
Pietzsch J, Julius U, Nitzsche S, Hanefeld M. In vivo evidence for increased apolipoprotein A-I catabolism in subjects with impaired glucose tolerance. Diabetes. 1998;47(12):1928-1934. doi:10.2337/diabetes.47.12.1928
Impact de 4 définitions différentes utilisées pour l’évaluation de la prévalence du syndrome métabolique dans les soins de santé primaires : Projet allemand sur les risques métaboliques et cardiovasculaires (GEMCAS) - PMC. Accessed March 1, 2025.
Osuji CU, Nzerem BA, Dioka CE, Onwubuya EI. Metabolic syndrome in newly diagnosed type 2 diabetes mellitus using NCEP-ATP III, the Nnewi experience. Nigerian Journal of Clinical Practice. 2012;15(4):475. doi:10.4103/1119-3077.104530
Islam MdS, Wei P, Suzauddula M, et al. The interplay of factors in metabolic syndrome: understanding its roots and complexity. Molecular Medicine. 2024;30(1):279. doi:10.1186/s10020-024-01019-y
Kahn R, Buse J, Ferrannini E, Stern M. The Metabolic Syndrome: Time for a Critical Appraisal: Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2005;28(9):2289-2304. doi:10.2337/diacare.28.9.2289
Jaspers Faijer-Westerink H, Kengne AP, Meeks KAC, Agyemang C. Prevalence of metabolic syndrome in sub-Saharan Africa: A systematic review and meta-analysis. Nutr Metab Cardiovasc Dis. 2020;30(4):547-565. doi:10.1016/j.numecd.2019.12.012
Paramètre anthropométrique permettant de mieux prédire le syndrome métabolique dans le sud-ouest du Nigéria - PubMed. Accessed January 16, 2025.
Annani-Akollor ME, Laing EF, Addai-Mensah O, Fondjo LA, Adu EA, Owiredu EW. Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population. Heliyon. 2020;6(8):e04583. doi:10.1016/j.heliyon.2020.e04583
Ménopause et syndrome métabolique chez la femme tunisienne - Ben Ali - 2014 - BioMed Research International - Wiley Online Library. Accessed January 16, 2025.
Abourazzak F, Talbi S, Lazrak F, et al. Does metabolic syndrome or its individual components affect pain and function in knee osteoarthritis women? Curr Rheumatol Rev. Published online May 21, 2015.
Okafor CI. The metabolic syndrome in Africa: Current trends. Indian J Endocrinol Metab. 2012;16(1):56-66. doi:10.4103/2230-8210.91191
Prévalence du syndrome métabolique et différences entre les sexes - PubMed. Accessed March 1, 2025.
W Z, M AE, Y Z, et al. Metabolic Syndrome, Independent Predictor for Coronary Artery Disease. Clinical laboratory. 2015;61(10). doi:10.7754/clin.lab.2015.150219
Acidocétose chez les diabétiques de type 1 : 73 cas à Dakar - PubMed. Accessed March 1, 2025.
Vg A, Vi B, An P, et al. The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study. Diabetes, obesity & metabolism. 2005;7(4). doi:10.1111/j.1463-1326.2004.00409.x
Acidocétose chez les diabétiques de type 1 : 73 cas à Dakar - PubMed. Accessed March 1, 2025.
Khadilkar A, Oza C, Mondkar SA. Insulin Resistance in Adolescents and Youth With Type 1 Diabetes: A Review of Problems and Solutions. Clinical Medicine Insights Endocrinology and Diabetes. 2023;16:11795514231206730. doi:10.1177/11795514231206730
Cisse F, Mehreza A, Thiam S, Lamkinsi T, Ndiaye A, Samba A, Coly NF, Soumah IY, Diedhiou F, Agossou HHM, Diallo-Agne F, Diatta A, & Sall ND. (2020). Etude de la prevalence du syndrome metabolique dans une population adulte Senegalaise / study of the prevalence of metabolic syndrome in Senegalese population. RAMReS2S - CRUFAOCI, 2(2), 1–7.
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Copyright (c) 2025 Suitambaye Noubaramadji Yamti, Abel Dafogo Djibagaou, Koutaya Dezoumbe, Amine Akouya, Zita Aleyo Nodjikouambaye, Andrillene Laure Detou Wondeu, Brahim Boy Otchom, Sabrina Atturo, Giulia Cappelli, Vittorio Colizzi

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