Mini Review: The Potential of Piperine in Black Pepper in Improving Brain Work

Authors

  • Dewi Yuniasih Universitas Ahmad Dahlan, Yogyakarta
  • Dandy Dewanto P Faculty of Medicine, Ahmad Dahlan University, Yogyakarta , Indonesia
  • Putri Kinanthi Faculty of Medicine, Ahmad Dahlan University, Yogyakarta , Indonesia
  • Nurul Aqidatul K Faculty of Medicine, Ahmad Dahlan University, Yogyakarta , Indonesia
  • Naila Sistharani Faculty of Medicine, Ahmad Dahlan University, Yogyakarta , Indonesia

Keywords:

Mini Review; Potential of Piperine; Black Pepper; Brain Work; Cognitive

Abstract

This study aims to determine the effect of piperine as an antidepressant and the potential to improve brain cognitive function. Researchers conducted a literature review related to piperine's potential for brain work using databases such as PubMed, Google Scholar, Cochrane Library. Search the relevant research literature using the keywords "Piperine in black pepper" or "piperine and brain effects". One of our conclusions is that piperine's cognitive-enhancing effects may occur in part through its cytoprotective and AChE inhibitory effects in the hippocampus.

Author Biography

Dewi Yuniasih, Universitas Ahmad Dahlan, Yogyakarta

References

Annu. Rev. Clin. Psychol. (2005). Stress and Depression. Los Angeles, California: Annual Review.

Christian Rafael Quijia, M. C. (2019). Characteristics, Biological Properties and Analytical Methods of Piperine : A Review. Critical Reviews in Analytical Chemistry, 1-16.

Emad M Abdallah, W. M. (2018). Black pepper fruit (Piper nigrum L.) as antibacterial agent: A mini-revirew. Journal of Bacterial & Mycology: Open Access, 141-1545.

Hidayati, L. N., & Harsono, M. (2021). Tinjauan Literatur Mengenai Stres Dalam Organisasi. Jurnal Ilmu Manajemen, 18(1), 20-30.

Jintanaporn, dkk. (2008). Piperine, the potential functional food for mood and cognitive disorders, Food and Chemical Toxicology. 46: 3106–3110.

John Wiley and Sons Inc., pp. 2717–2725. Shen, Y. and Li, R. 1995. ‘The role of neuropeptides in learning and memory: Possible mechanisms’, Medical Hypotheses, 45(6), pp. 529–538.

K Vasavirama, M. U. (2014). Piperine : A Valuable Alkaloid From Piper Species. International Journal of Pharmacy and Pharmaceutical Sciences, 34-38.

Larasati, Ratih. (2016). Pengaruh Stres Pada Kesehatan Jaringan Periodontal. Surabaya: Jurnal Skala Husada. Volume 13.

Pennapa Chonpathompikunlert, Jintanaporn Wattanathorn, Supaporn Muchimapura. (2010). Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 48(3):798-802

Plein, L. M. and Rittner, H. L. (2018). ‘Opioids and the immune system – friend or foe’, British Journal of Pharmacology.

Tianjing Ren, Z. Z. (2019). Role of Piperine in CNS disease: pharmacodynamics, pharmacokinetics and drug interactions. Expert Opinion on Drug Metabolism & Toxicology.

Veening, J. G. and Barendregt, H. P. (2015). The effects of Beta-Endorphin: State change modification, Fluids and Barriers of the CNS. BioMed Central Ltd.

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Published

2021-12-30