PLANT ANATOMY Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson AND Tithonia Diversifolia (Hemsley) A. Grays AS REDUCING SUGAR CONTENT
DOI:
https://doi.org/10.12928/jbns.v6i1.15734Keywords:
Plant anatomy, Reducing sugar, Smallanthus sonchifolius, Tithonia diversifoliaAbstract
Currently, the number of people with diabetes mellitus worldwide is increasing. According to the 11th edition of the International Diabetes Federation (IDF) Diabetes Atlas (2024/2025), approximately 19.5–20.4 million Indonesian adults will be living with diabetes by 2025. The plants Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia Diversifolia (Hemsley) A. Gray are currently the subject of public discussion due to their usefulness in lowering blood sugar levels. The purpose of this study was to distinguish the macroscopic and microscopic identification characteristics and the presence of chemical compounds in the roots, stems, and leaves of Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia Diversifolia (Hemsley) A. Gray. The research method was purely experimental, involving macroscopic identification characteristics, microscopic characteristics, and chemical testing of Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia Diversifolia (Hemsley) A. Gray plants. Results and Discussion Macroscopic identification characteristics of Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia diversifolia (Hemsley) A. Gray, which have taproots, round stems that are moist, soft, and woody, leaves with wavy edges, and alternate or opposite leaf arrangement, with some being scattered. Microscopic identification characteristics show the presence of calcium oxalate crystals. The chemical content of the leaves, bark, and roots of Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia diversifolia (Hemsley) A. Gray contains saponins, polyphenols, flavonoids, and alkaloids, indicating that flavonoids act as antioxidants that can increase insulin sensitivity.Conclusion: The macroscopic and microscopic identification characteristics of the plants Smallanthus Sonchifolius (Poeppig & Endlicher) H. Robinson and Tithonia diversifolia (Hemsley) A. Gray are taprooted and tuberous, with brown taproots and no tubers, round stems that are soft, moist, and sometimes woody. The leaves have wavy edges, an opposite and alternate arrangement, and are scattered. The presence of epidermis, stomata, parenchyma, sclerenchyma, trichomes, and vascular bundles can be seen in the cross-section of the stem and leaves. The chemical content includes saponins, flavonoids, polyphenols, and alkaloids.
References
Alhujaily, M., Dhifi, W., & Mnif, W. (2022). An overview of the potential of medicinal plants used in the development of nutraceuticals for the management of diabetes mellitus: Proposed biological mechanisms. Processes, 10(10), 2044.
Dewi, T. A., & Haryoto, H. (2025). Antidiabetic activity of ethanol leaf extract fractions from yacon (Smallanthus sonchifolius). CERATA Journal of Pharmaceutical Sciences
Erwin et al. (2023). Determination of Total Flavonoid Content (TFC) and Antioxidant Activity of Insulin Plants. Journal of Science and Health.
Febrianti, I., Erwin, & Pasaribu, S. P. (2021). Phytochemical screening and bioactivity of leaf, stem, and bark extracts of the insulin plant (Smallanthus sonchifolius). Proceedings of the National Chemistry Seminar.
Fitriyanto, R. E., Sugiarto, & Ardiyanto, D. T. (2020). Effects of methanol extracts of insulin leaves (Tithonia diversifolia (Hemsley) A. Gray) on insulin resistance and secretion of alloxan-induced obese diabetic rats. JKKI: Indonesian Journal of Medicine and Health,
International Diabetes Federation. IDF Diabetes Atlas 11th Edition 2024/2025: Prevalence of Diabetes in Indonesia. (IDF Report) — used as source for figures 19.5 – 20.4). https://diabetesatlas.org/data-by-location/country/indonesia/
Kartika, R., & Yuliani, D. (2023). Analysis of the anatomy, secretory structure, and histochemistry of Tithonia diversifolia (Hemsley) A. Gray leaves. IPB Repository.
Malek, A., Cepeda, F., Kerner, T., Nowakowska, B., Birhan, F., & Zghebi, H. (2023). A Systematic Review of Type 2 Diabetes: Chronic Metabolic Disorder. Journal of International Journal of Endocrinology and Disorders, V2(2).
Ministry of Health. (2025, November 9). Prevention of obesity and diabetes is key to reducing disease burden. November 9. Ministry of Health of the Republic of Indonesia.
Nuroini, A., et al. (2018). Testing the Effectiveness of Moonflower Leaf Extract (Tithonia diversifolia) on Lowering Blood Glucose Levels. Scientific Journal of Pharmacy
Oda, S., et al. (2016). "Morphological and Genetic Characteristics of Yacon (Smallanthus sonchifolius) Cultivated in Japan". Journal of Plant Studies.
Prasetyo, R. (2021). Antidiabetic effects of Tithonia diversifolia leaf, flower, and root extracts on alloxan-induced Wistar rats. Health Journal.
Rahman, N. F., Nursamsiar, M., Megawati, H., Handayani, C. A. M. S. (2021). Total Phenolic and Flavonoid Contents and Antioxidant Activity of Kembang Bulan Leaves (Tithonia diversifolia). Indonesian Journal of Pharmaceutical Science and Technology.
Ramadhani, M.A., Anita Kumala Hati, Novel Fibriani Lukitasari, & Armin Hari Jusman (2025). Phytochemical Screening and Determination of Total Flavonoid and Total Phenolic Content of Insulin Leaf Extract (Tithonia diversifolia). Indonesian Journal of Pharmacy and Natural Product.
Raven, P. H., Evert, R. F., & Eichhorn, S. E. (2018). Biology of plants (8th ed.). New York: W.H. Freeman and Company.
Unesa Journal of Chemistry (2025) Pharmacological Effects and Toxic Effects of Yacon Leaves (Smallanthus sonchifolius).
Sari, N., et al. (2020). The Potential of Tannin Compounds in Lowering Blood Sugar Levels: A Review of Articles. Journal of Clinical and Community Pharmacy.
Sintowati, R., Nurhayati, N., Daselva, S., & Prasetyo, R. (2021). Antidiabetic effects of leaf, flower, and root extracts of kembang bulan (Tithonia diversifolia). Journal of Health.
Saputri, S., & Sa’ad, M. (2023). Determination of phenolic and flavonoid levels in insulin leaf (Smallanthus sonchifolius) fractions using UV-Vis spectrophotometry. Pharmacy Medical Journal.
Shelef, O., Gross, A., & Rachmilevitch, S. (2017). Role of plants in a constructed wetland: Current and new perspectives. Ecological Engineering, 98, 405–419.
Silva, I. F. da, et al. (2024). Effects of Smallanthus sonchifolius flour on metabolic parameters: Systematic review highlighting flavonoids, sesquiterpene lactones, and inulin. Pharmaceuticals.
Suyono Saputri, D. et al. (2025). The effect of solvent variation on insulin leaf extract (Smallanthus sonchifolius) as an antioxidant. Jurnal Farmasi Medica.
Taiz, L., Zeiger, E., Møller, I. M., & Murphy, A. (2015). Plant physiology and development. Sunderland: Sinauer Associates
Triastuti et al. (2025). The effectiveness of yakon leaf extract administration as antihyperglycemic therapy in mice. Herb-Medicine Journal.
Yan, X., et al. (2019). Smallanthus sonchifolius: A Review of Its Phytochemistry, Pharmacology and Nutritional Value. Frontiers in Pharmacology
Ziimmet, P., Alberti, K. G. M. M., & Shaw, J. (2022). Diabetes Mellitus and Its Metabolic Complications: The Role of Adipose Tissues. International Journal of Molecular Sciences, 22(14), 7644.
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