Evaluation of the Rationality of Antihypertensive Drug Use in Hypertension Patients at Peusangan Siblah Krueng Public Health Center, Bireuen District
DOI:
https://doi.org/10.12928/admj.v6i2.14430Keywords:
Rationality, Antihypertensive, Hypertension, 4T, Primary Health Center.Abstract
Hypertension is a chronic disease with a high prevalence and a significant risk of serious complications if not properly managed. The aim of this study was to evaluate the rational use of antihypertensive drugs in hypertensive patients at Peusangan Siblah Krueng Public Health Center, Bireuen District, based on the criteria of appropriate indication, appropriate patient, appropriate drug, and appropriate dose according to JNC VIII guidelines. This was a descriptive observational study with a retrospective approach using medical records of hypertensive patients in 2023. A total of 185 patients were selected through purposive sampling based on inclusion and exclusion criteria. Data collected included patient identity, diagnosis, type of antihypertensive drugs, dosage, and administration. Rationality was evaluated using the 4T classification (appropriate indication, patient, drug, and dose) in accordance with JNC VIII guidelines. The results showed that appropriateness of indication and patient both reached 100%. Appropriateness of drug was 96.8%, with the majority of patients receiving amlodipine as the main therapy. Appropriateness of dose was 98.9%, with a small proportion of inappropriateness observed in patients with comorbid diabetes mellitus. Overall, the use of antihypertensive drugs in hypertensive patients at Peusangan Siblah Krueng Public Health Center, Bireuen District, can be categorized as rational based on the 4T criteria, although some discrepancies remain in drug selection and dosage, particularly among patients with comorbidities.
References
Iqbal M, Triyandi R, Sukoha A, et al. Bahaya Hipertensi dan Komplikasinya : Sebuah Penyakit Pemutus Kebahagian dan Harapan Hidup. J Pengabdi Masy Ruwa Jurai. Published online 2019:127.
Asyura F. Hubungan Dukungan Keluarga Dengan Derajat Hipertensi Pada Pasien Hipertensi Di Gampong Meunasah Tambo Kecamatan Peudada Kabupaten Bireuen. J Keperawatan STIKES Muhammadiyah Lhokseumawe. 2015;2:1-2.
Kementerian Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 75 Tahun 2013 Tentang Angka Kecukupan Gizi Yang Dianjurkan Bagi Bangsa Indonesia.; 2013:1-10.
Rawat P, Di J, Sakit R, Kediri DI. Java Health Journal ||. 2023;10(3):1-11.
Ekaningtyas A, Wiyono W, Mpila D. Evaluasi Penggunaan Obat Antihipertensi pada Pasien Hipertensi di Puskesmas Kolongan Kabupaten Minahasa Utara. Pharmacon– Progr Stud Farm Fmipa, Univ Sam Ratulangi. 2021;10(4):1215-1221.
Aronow WS. Managing Hypertension in the elderly: What’s new? Am J Prev Cardiol. 2020;1:100001. doi:10.1016/j.ajpc.2020.100001
Hobbs FDR. The new British Hypertension Society guidelines: a view from primary care. J Hum Hypertens. 2000;14(4):223-225. doi:10.1038/sj.jhh.1000970
Mukti G, Harsono SB, Cahyo LM. Analisis Rasionalitas Penggunaan Obat Antihipertensi Pada Pasien Geriatri di Rumah Sakit X Periode Tahun 2023. 2024;10(2):389-396.
Diwati A, Sofyan O. Profil dan Rasionalitas Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Di Fasilitas Kesehatan Tingkat Pertama Periode Mei - Juli 2021. Maj Farm. 2023;19(1):1. doi:10.22146/farmaseutik.v19i1.80153
Muhammad Akib Yuswar. The Relationship Between The Rationality Of Prescribing And The Quality Of Life Of Hypertension Patients At The Central Siantan Health Center In Pontianak. Media Farm Indones. 2024;19(1). doi:10.53359/mfi.v19i1.251
Sari YK, Susanti ET. Hubungan jenis kelamin dengan kejadian hipertensi pada lansia di puskesmas nglegok kabupaten blitar. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery). 2016 Dec 1;3(3):262-5.
Bager JE, Manhem K, Andersson T, et al. Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary care. J Hum Hypertens. 2023;37(8):662-670. doi:10.1038/s41371-023-00801-5
Winanti Setia P, Arisandi D, Sari Wulan S. Evaluasi Rasionalitas Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Di Instalasi Rawat Jalan RSUD Dr . R . Goeteng Keejadian kasues peendeerita hipeerteensi di. Bina Cipta Husada. 2024;XX(2):1-14.
Whelton PK, Carey RM, Aronow WS, et al. Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertens (Dallas, Tex 1979). 2018;71(6):e13-e115. doi:10.1161/HYP.0000000000000065
WHO. Guideline for the Pharmacological Treatment of Hypertension in Adults. Vol 11. WHO; 2021.
Armstrong C. JNC8 guidelines for the management of hypertension in adults. Am Fam Physician. 2014;90(7):503-504.
Prajapat R, Jain I, Singh S, Singh S, Agarwal P. The effect of amlodipine on blood glucose level and its interaction with oral hypoglycemic drugs in albino rabbits. Int J Basic Clin Pharmacol. 2013;2(6):768. doi:10.5455/2319-2003.ijbcp20131218
DeGeeter M, Taylor SR, Cress J. Amlodipine-induced hyperglycaemia. Pract Diabetes. 2018;35(5):181-183. doi:10.1002/pdi.2189
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 yuziani yuziani
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
License and Copyright Agreement
In submitting the manuscript to the journal, the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal. Please also carefully read Ahmad Dahlan Medical Journal posting Your Article Policy.
- That it is not under consideration for publication elsewhere.
- That its publication has been approved by all the author(s) and by the responsible authorities - tacitly or explicitly - of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
Copyright
Authors who publish with Ahmad Dahlan Medical Journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
