THE CORRELATION BETWEEN HYPERTENSION AND COGNITIVE FUNCTION

Authors

  • Elvina Zuhir Faculty of Medicine and Health Sciences Universitas Abdurrab

DOI:

https://doi.org/10.12928/ijhr.v1i1.221

Keywords:

Cognitive Function, Dementia, Hypertension, MMSE, RPM

Abstract

Background: Rapid increase in Indonesia health development lead to increase in life expectancy. This demographical shift implicated in altering disease pattern to dominate be degenerative diseases, such as hypertension. Hypertension affected morbidity and mortality rate significantly. Hypertension also known to correlated with increasing risk in cerebrovascular diseases that continue to cognitive function disorders such as vascular dementia.

 

Objective: To know the relationship between hypertension and cognitive function.

Methods: Using cross-sectional design with comparative study. Blood pressure measured by using sphygmomanometer and stethoscope, while cognitive function measured by using Mini Mental State Examination (MMSE) and Raven Progressive Matrices (RPM). This research was held in M. Djamil Hospital, Puskesmas Nanggalo Siteba, Puskesmas Padang Pasir, Puskesmas Alai, Puskesmas Andalas, Puskesmas Seberang Padang dan Puskesmas Pauh with consecutive sampling technique

Result: There is no significant differentiation based on age and gender in hypertension and normotensive sample. There is significant differentiation in cognitive function in hypertension and norm tension sample (p-value< 0,05). Hypertension sample will have 7,8 times risk to had cognitive function disorders than normotensive sample (measured using MMSE; OR: 7,8). Hypertension sample will have 3,3  times risk to had cognitive function disorders than normotensive sample (measured using RPM; OR: 3,3).

Conclusion: There is significant differentiation in cognitive function in hypertension and normotensive sample. Hypertension subject will have 3,3 to 7,8 times risk to had cognitive function disorders than normotensive


References

1. AHA. High Blood Pressure Increase Risk of Reduced Function in Older Ages. 2007. (http://www.americanheart.org/presenter. Downloaded 28 september 2009)
2. Azwar A. Epidemiologi Hipertensi, Simposium Berbagai Aspek Hipertensi, FKUI, Jakarta; 13 Juli 1985
3. Bappenas RI. Tahun 2005 Angka Harapan Hidup Penduduk Indonesia. http://www.bappenas.go.id/node/142/1277/tahun 2025/ Angka Harapan Hidup. 2000.
4. Chiang CE and Chen CH. Hypertension in the Asia Pacific region. Journal of Human Hypertension, 2008, 22, 441-443
5. Dai W, Lopez OL, Carmichael OT, Becker JT, Kuller LH, Gach HM. Abnormal Regional Cerebral Blood Flow in Cognitively Normal Elderly Subjects with Hypertension. Stroke, 2008. ;39:349-354
6. Departemen Kesehatan RI. Laporan Hasil Riset Kesehatan Dasar (RISKESDAS) Nasional Badan Penelitian dan Pengembangan Kesehatan, 2007; v-vx.
7. Elias MF, Robbins MA, Schultz NR, Streeten DH and Elias PK. Clinical Significance of Cognitive Performance by Hypertensive Patients. Journal of America Heart Association, 1987 ;9;192-197
8. Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, and Alhainen K et al. Midlife Vascular Risk Factors and Alzheimer’s Disease in Later Life: Longitudinal, Population Based Study. MBJ, Jun, 200116:322(7300):1447-1451
9. Knecht S, Wersching H, Lohmann H, Bruchmann M, Duning T, Dziewas R et al. High-Normal Blood Pressure Is Associated With Poor Cognitive Performance. Hypertension, 2008 ;51:663-668
10. Kuusisto J, Koivisto K, Mykkanen L, Helkala EL, Vanhanen M, Hanninnen T et al. Essential Hypertension and Cognitive Function. The Role of Hyperinsulinemia. Hypertension, 1993; 22:771-779
11. Perdossi. Diagnosis Dini Dan Penatalaksanaan Demensia. Kelompok Studi Neuro-behaviour, 2007, 1-8.
12. Reitz C, Tang MX, Manly J, Mayeux R, Luchsinger JA. Hypertension and the Risk of Mild Cognitive Impairment. Arch Neurol, 2007 ;64(12):1734-1740
13. Seux ML, Thijs L, Forette F, Staessen JA, Birkenhager WH, Bulpitt CJ et al. Correlates of Cognitive Status of Old Patients With Isolated Systolic Hypertension: the Syst-Eur Vascular Dementia Project. Journal of Hypertension,1998, 16:963-9
14. Tzourio C, Dufouil C, Ducimetiere P, Alperovitch A. Cognitive Decline in Individuals With High Blood Pressure: a Longitudinal Study in the Elderly. EVA Study Group. Epidemiology of Vascular Aging. Neurology, Dec, 1999 ;10;53(9);52

Downloads

Published

2018-08-23

Issue

Section

Articles